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Prof. Jeehyun Kwag's paper accepted in Science Advances
Author Administrator (IP: *.152.74.116) Date 2020-04-23 17:29 Views 968
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Prof. Jeehyun Kwag's research paper, 'Distinct roles of parvalbumin and somatostatin interneurons in gating the synchronization of spike times in the neocortex'  was accepted in Science Advances.  


Title: 
Distinct roles of parvalbumin and somatostatin interneurons in gating the synchronization of spike times in the neocortex

Abstract: 
Synchronization of precise spike times across multiple neurons carries information about sensory stimuli. Inhibitory interneurons are suggested to promote this synchronization, but it is unclear whether distinct interneuron su
btypes provide different contributions. To test this, we examined single-unit recordings from barrel cortex in vivo and used optogenetics to determine the contribution of parvalbumin (PV)– and somatostatin (SST)–positive interneurons to the synchronization of spike times across cortical layers. We found that PV interneurons preferentially promote the synchronization of spike times when instantaneous firing rates are low (<12 Hz), whereas SST interneurons preferentially promote the synchronization of spike times when instantaneous firing rates are high (>12 Hz). Furthermore, using a computational model, we demonstrate that these effects can be explained by PV and SST interneurons having preferential contributions to feedforward and feedback inhibition, respectively. Our findings demonstrate that distinct subtypes of inhibitory interneurons have frequency-selective roles in the spatiotemporal synchronization of precise spike times.

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Research
Prof. Jong-Hwan Lee's paper accepted in NeuroImage
Prof. Jong-Hwan Lee's paper accepted in NeuroImage
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2020-09-02

Prof. Jong-Hwan Lee's paper accepted in NeuroImage
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 link to news: http://korea.ac.kr/user/boardList.do?boardId=474633&command=albumView&page=1&boardSeq=488752&id=university_060108000000

2020-08-12

Prof. Heung-Il Suk's paper accepted in IEEE Transactions on Neural Networks and Learning Systems
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Prof. Heung-Il Suk's research paper, 'Uncertainty-Gated Stochastic Sequential Model for EHR Mortality Prediction' was accepted in IEEE Transactions on Neural Networks and Learning Systems.Title: Uncertainty-Gated Stochastic Sequential Model for EHR Mortality Prediction Abstract: Electronic health records (EHR) are characterized as non-stationary, heterogeneous, noisy, and sparse data; therefore, it is challenging to learn the regul…

2020-08-07

Prof. Heung-Il Suk's paper. selected as Most Downloaded Article in the Past Year
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2020-08-03

Prof. Byoung-Kyong Min's paper published at NeuroImage
Prof. Byoung-Kyong Min's paper published at NeuroImage
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2020-06-15

Prof. Jeehyun Kwag's paper accepted in Chaos
Prof. Jeehyun Kwag's paper accepted in Chaos
Prof. Jeehyun Kwag's research paper, 'Distinct subtypes of inhibitory interneurons differentially promote the propagation of rate and temporal codes in the feedforward neural network' was accepted in Chaos.  link to the publication: https://aip.scitation.org/doi/full/10.1063/1.5134765Title: Distinct subtypes of inhibitory interneurons differentially promote the propagation of rate and temporal codes in the feedforward neu…

2020-05-29

Prof. Jeehyun Kwag's paper accepted in Science Advances
Prof. Jeehyun Kwag's paper accepted in Science Advances
Prof. Jeehyun Kwag's research paper, 'Distinct roles of parvalbumin and somatostatin interneurons in gating the synchronization of spike times in the neocortex'  was accepted in Science Advances.  Publication Link: https://advances.sciencemag.org/content/6/17/eaay5333/Title: Distinct roles of parvalbumin and somatostatin interneurons in gating the synchronization of spike times in the neocortexAbstract: Synchron…

2020-04-23

Prof. Byoung-Kyong Min's paper accepted in Trends in Biotechnology
Prof. Byoung-Kyong Min's paper accepted in Trends in Biotechnology
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2020-03-09

Prof. Jeehyun Kwag's paper accepted in Brain Structure and Function
Prof. Jeehyun Kwag's paper accepted in Brain Structure and Function
Prof. Jeehyun Kwag's research paper, 'Dissociation of Somatostatin and Parvalbumin Interneurons Circuit Dysfunctions Underlying Hippocampal Theta and Gamma Oscillations impaired by Amyloid β Oligomers in Vivo' was accepted in Brain Structure and Function. Publication Link: https://link.springer.com/article/10.1007/s00429-020-02044-3Title: Dissociation of somatostatin and parvalbumin interneurons circuit dysfunctions underlyin…

2020-03-02

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