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Prof. Jeehyun Kwag's paper accepted in Chaos
Author Administrator (IP: *.152.74.116) Date 2020-05-29 16:14 Views 51
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Prof. Jeehyun Kwag's research paper, 'Distinct subtypes of inhibitory interneurons differentially promote the propagation of rate and temporal codes in the feedforward neural network' was accepted in Chaos.  


Title: 
Distinct subtypes of inhibitory interneurons differentially promote the propagation of rate and temporal codes in the feedforward neural network

Abstract: 
Sensory information is believed to be encoded in neuronal spikes using two different neural codes, the rate code (spike firing rate) and the temporal code (precisely-timed spikes). Since the sensory cortex has a highly hierarchical feedforward structure, sensory information-carrying neural codes should reliably propagate across the feedforward network (FFN) of the cortex. Experimental evidence suggests that inhibitory interneurons, such as the parvalbumin-positive (PV) and somatostatin-positive (SST) interneurons, that have distinctively different electrophysiological and synaptic properties, modulate the neural codes during sensory information processing in the cortex. However, how PV and SST interneurons impact on the neural code propagation in the cortical FFN is unknown. We address this question by building a five-layer FFN model consisting of a physiologically realistic Hodgkin–Huxley-type models of excitatory neurons and PV/SST interneurons at different ratios. In response to different firing rate inputs (20–80 Hz), a higher ratio of PV over SST interneurons promoted a reliable propagation of all ranges of firing rate inputs. In contrast, in response to a range of precisely-timed spikes in the form of pulse-packets [with a different number of spikes (α, 40–400 spikes) and degree of dispersion (σ, 0–20 ms)], a higher ratio of SST over PV interneurons promoted a reliable propagation of pulse-packets. Our simulation results show that PV and SST interneurons differentially promote a reliable propagation of the rate and temporal codes, respectively, indicating that the dynamic recruitment of PV and SST interneurons may play critical roles in a reliable propagation of sensory information-carrying neural codes in the cortical FFN.
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Research
Prof. Heung-Il Suk's paper. selected as Most Downloaded Article in the Past Year
Prof. Heung-Il Suk's paper. selected as Most Downloaded Article in the Past Year
 Prof. Heung-Il Suk's paper on "Deep Learning in Medical Image Analysis" was selected as "Most Downloaded Article in the Past Year" in the Annual Review of Biomedical Engineering (2019-JCR-IF: 15.541). Please refer to the link for more information. https://www.annualreviews.org/journal/bioeng

2020-08-03

Prof. Byoung-Kyong Min's paper published at NeuroImage
Prof. Byoung-Kyong Min's paper published at NeuroImage
Prof. Byoung-Kyong Min's research paper, 'Thalamocortical Inhibitory Dynamics Support Conscious Perception' was publishsed at NeuroImage. Link to the publication: https://doi.org/10.1016/j.neuroimage.2020.117066 Title: Thalamocortical Inhibitory Dynamics Support Conscious Perception Abstract:Whether thalamocortical interactions play a decisive role in conscious perception remains an open question. We presented rapid red/g…

2020-06-15

Prof. Jeehyun Kwag's paper accepted in Chaos
Prof. Jeehyun Kwag's paper accepted in Chaos
Prof. Jeehyun Kwag's research paper, 'Distinct subtypes of inhibitory interneurons differentially promote the propagation of rate and temporal codes in the feedforward neural network' was accepted in Chaos.  link to the publication: https://aip.scitation.org/doi/full/10.1063/1.5134765Title: Distinct subtypes of inhibitory interneurons differentially promote the propagation of rate and temporal codes in the feedforward neu…

2020-05-29

Prof. Jeehyun Kwag's paper accepted in Science Advances
Prof. Jeehyun Kwag's paper accepted in Science Advances
Prof. Jeehyun Kwag's research paper, 'Distinct roles of parvalbumin and somatostatin interneurons in gating the synchronization of spike times in the neocortex'  was accepted in Science Advances.  Publication Link: https://advances.sciencemag.org/content/6/17/eaay5333/Title: Distinct roles of parvalbumin and somatostatin interneurons in gating the synchronization of spike times in the neocortexAbstract: Synchron…

2020-04-23

Prof. Byoung-Kyong Min's paper accepted in Trends in Biotechnology
Prof. Byoung-Kyong Min's paper accepted in Trends in Biotechnology
Prof. Byoung-Kyong Min's research paper, 'New Cognitive Neurotechnology Facilitates Studies of Cortical-Subcortical Interactions' was accepted in Trends in Biotechnology. Title: New Cognitive Neurotechnology Facilitates Studies of Cortical-Subcortical Interactions Abstract:Most of the studies employing neuroimaging have focused on cortical and subcortical signals individually to obtain neurophysiological signatures of cognitiv…

2020-03-09

Prof. Jeehyun Kwag's paper accepted in Brain Structure and Function
Prof. Jeehyun Kwag's paper accepted in Brain Structure and Function
Prof. Jeehyun Kwag's research paper, 'Dissociation of Somatostatin and Parvalbumin Interneurons Circuit Dysfunctions Underlying Hippocampal Theta and Gamma Oscillations impaired by Amyloid β Oligomers in Vivo' was accepted in Brain Structure and Function. Publication Link: https://link.springer.com/article/10.1007/s00429-020-02044-3Title: Dissociation of somatostatin and parvalbumin interneurons circuit dysfunctions underlyin…

2020-03-02

Prof. Jeehyun Kwag's paper accepted in BMC Biology
Prof. Jeehyun Kwag's paper accepted in BMC Biology
Prof. Jeehyun Kwag's research paper, 'Optogenetic activation of parvalbumin and somatostatin interneurons selectively restores theta-nested gamma oscillations and oscillation-induced spike timing-dependent long-term potentiation impaired by amyloid β oligomers' was accepted in BMC Biology. Title: Optogenetic activation of parvalbumin and somatostatin interneurons selectively restores theta-nested gamma oscillations and oscillation…

2020-03-02

Prof. Heung-Il Suk's paper accepted in NeuroImage
Prof. Heung-Il Suk's paper accepted in NeuroImage
Prof. Heung-Il Suk's research paper, 'Toward an Interpretable Alzheimer's Disease Diagnostic Model with Regional Abnormality Representation via Deep Learning' was accepted in NeuroImage.  Title: Toward an Interpretable Alzheimer's Disease Diagnostic Model with Regional Abnormality Representation via Deep Learning  Abstract: In this paper, we propose a novel method for magnetic resonance imaging based Alzheimer's disease (…

2019-08-20

Prof.Jae-Ho Han’s paper accepted in IEEE Transactions on Image Processing
Prof.Jae-Ho Han’s paper accepted in IEEE Transactions on Image Processing
Prof. Jae-Ho Han’s new research on `Deep Neural Network Regression for Automated Retinal Layer Segmentation in Optical Coherence Tomography Images` was accepted in IEEE Transactions on Image Processing.  Title: Deep Neural Network Regression for Automated Retinal Layer Segmentation in Optical Coherence Tomography ImagesAbstract: Segmenting the retinal layers in optical coherence tomography (OCT) images helps to quantify the …

2019-07-24

Prof. Seong-Whan Lee's paper accepted in IEEE Transactions on Intelligent Transportation Systems
Prof. Seong-Whan Lee's paper accepted in IEEE Transactions on Intelligent Transp…
Prof. Seong-Whan Lee's new research, Coarse-to-Fine Deep Learning of Continuous Pedestrian Orientation Based on Spatial Co-occurrence Feature was accepted in IEEE Transactions on Intelligent Transportation Systems. Title: 'Coarse-to-Fine Deep Learning of Continuous Pedestrian Orientation Based on Spatial Co-occurrence Feature Abstract: The continuous orientation estimation of a moving pedestrian is a crucial issue in auto…

2019-05-02

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